Adverse Effects of Antiepileptic Drug Lamotrigine and Oral Implications: Case Report

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Adverse Effects of Antiepileptic Drug Lamotrigine and Oral Implications: Case Report

Here, we report on a patient who presented with extensive oral lesions. The treatment with lamotrigine is described.The patient presented with bilateral facial swellings and mental space swelling with actively draining extra oral sinus tract in the central chin area. Dental medicine professionals should be aware of the risks involved with using this medication, and should recognize the populati...

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Active epilepsy with recurrent seizures is associated with a range of well-documented unfavourable consequences. Nevertheless, adverse metabolic effects of antiepileptic drug (AED) treatments have only recently received attention. Such effects may be subtle, insidious, take many years to become clinically apparent, and may have a negative impact on general health for many decades. Unfortunately...

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Effect of antiepileptic drug comedication on lamotrigine concentrations

AIM To estimate the effect size of concomitant antiepileptic therapy on the concentrations of lamotrigine, a drug often prescribed in combination with other antiepileptic drugs (AED), which can act as enzyme inducers or inhibitors. METHODS A total of 304 patients with epilepsy, aged 18-70 years, were divided into a lamotrigine monotherapy group and groups receiving lamotrigine with AEDs that ...

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A 55-year-old female with no physical problems was initially hospitalized for psychotic mania but soon discharged. A month later she was rehospitalized for bipolar depression and treated with lamotrigine (25 mg/day), olanzapine (10 mg/day), and lorazepam (0.5 mg/day). On day 22, lamotrigine was stopped because of neutropenia. On the same day, the patient developed skin rashes with pruritus, whi...

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ژورنال

عنوان ژورنال: Acta Stomatologica Croatica

سال: 2017

ISSN: 0001-7019,1846-0410

DOI: 10.15644/asc51/2/8